Tesamorelin 10 Mg

Tesamorelin 10 Mg About

Tesamorelin is a synthetic 44-amino acid peptide analogue of Growth Hormone-Releasing Hormone (GHRH), also known as a growth hormone-releasing factor (GRF) analog.

It is primarily used to reduce excess visceral (deep abdominal) fat in adults with HIV-associated lipodystrophy. It is the first medication specifically approved for this purpose.

• It consists of the full 44-amino acid sequence of human GHRH, modified at the N-terminus with a trans-3-hexenoyl group attached to the tyrosine residue. This modification enhances its stability and resistance to enzymatic breakdown.
• Molecular Formula (free base): CHNOS
• Molecular Weight: Approximately 5,136 g/mol
• It is typically supplied as tesamorelin acetate for subcutaneous injection.

Tesamorelin binds to GHRH receptors in the pituitary gland, stimulating the natural pulsatile release of endogenous growth hormone (GH). This increases levels of insulin-like growth factor-1 (IGF-1), which promotes lipolysis (fat breakdown), particularly targeting visceral abdominal fat, while supporting overall body composition regulation.

• Reduction of excess abdominal fat in HIV patients with lipodystrophy.
• It is administered as a daily subcutaneous injection, typically 2 mg into the abdomen.

• Injection site reactions (redness, swelling, itching, pain)
• Joint or muscle pain
• Fluid retention (edema)
• Itching or tingling sensations
• Possible changes in blood sugar or IGF-1 levels

Tesamorelin is generally well-tolerated when used as prescribed. It is a prescription medication and should only be used under medical supervision.